Formic Acid
Formic acid (HCOOH) is naturally-occurring, flammable, corrosive, organic, and the simplest carboxylic acid. Used as a hydride ion source in synthetic organic chemistry, a mobile phase component in HPLC, a preservative/antibacterial agent in agriculture, etc.
Formic or methanoic acid (CAS: 64-18-6; PubChem ID: 284) is a colorless organic acid with the formula HCOOH. At ambient temperatures, it has a strong, penetrating odor, like acetic acid. Used in chemical synthesis as an intermediate, this simple carboxylic acid is miscible in water and most organic solvents and is somewhat hydrocarbon-soluble.
Formic acid occurs naturally in the venom of some ants and bees. Formate, the conjugate base of formic acid, also occurs naturally in bodily fluids following methanol poisoning.
Formic acid is a source of hydride ion in synthetic organic chemistry, as in the Eschweiler-Clarke and Leuckart-Wallach reactions. It is also a useful component of the mobile phase in reversed-phase high-performance liquid chromatography (RP-HPLC) for peptides, proteins, and intact viruses.
Although formic acid is easily metabolized and eliminated, it can have toxic effects. Methanol metabolism produces formic acid and formaldehyde, which are responsible for the optic nerve damage that results from methanol poisoning. Chronic exposure in humans may cause kidney damage and skin allergies in some people.
In diluted forms, formic acid and formate esters are used as artificial flavorings and perfume additives. In higher concentrations, formic acid is flammable, and skin and eye contact with concentrated liquid or vapors is dangerous.
In agriculture, formic acid is used as a preservative and antibacterial agent and by beekeepers to kill mites. It is useful in leather tanning, textile dyeing and finishing, and in rubber production. Formic acid replaces mineral acids in limescale removers and other cleaning products.
Sigma Aldrich Fine Chemicals Biosciences Formic acid >=95%, FCC, FG | 64-18-6 | MFCD00003297 | 25KG
Formic acid >=95%, FCC, FG | Purity: >=95% | Mol Wt: 46.03 | 64-18-6 | MFCD00003297 | 25KG
Medchemexpress LLC Bisindolylmaleimide IX formic | 00-00-0 | 96.0% | C26H25N5O4S | 10MG
Ro 31-8220 formic is a small-molecule research reagent that acts as a potent, cell-permeable inhibitor of protein kinase C (PKC) and several other kinases. It is used in biochemical and cellular studies to probe PKC-dependent signaling, kinase selectivity, and downstream pathway effects such as JNK activation and c-Jun induction.
- Potent PKC inhibition with low-nanomolar IC50s.
- Inhibits multiple kinases for broad pathway interrogation.
- Cell-permeable for use in cellular assays.
- High purity solid with characteristic orange to red color.
- Stable when stored sealed at -20°C; in solvent can be stored at -80°C for extended periods.
- Available in small milligram pack sizes suitable for research use.
Medchemexpress LLC Lcc-12 formic | 3029253-76-4 | 99.2% | 460.57 g/mol | C18H40N10O4 | 10 MG
LCC-12 formic is a research-grade small molecule probe (a dimer of metformin) used to modulate mitochondrial copper(II) and study inflammation and metabolic pathways in cellular and animal models.
- Targets mitochondrial copper(II) and reduces the NAD(H) pool.
- Reduces inflammation in mouse models of bacterial and viral infection.
- Serves as a tool to study metabolic disease, cell plasticity, and epigenetic programming.
- High purity and characterized molecular properties for reliable experimental use.
- Compatible with storage at -20°C; in solution store at -80°C for long-term stability.
Sigma Aldrich Fine Chemicals Biosciences SIGMA ALDRICH FINE CHEMICALS BIOSCIENCES
NC3982132 FORMIC ACID 98-100 FOR HPLC L
Sigma Aldrich Fine Chemicals Biosciences Formic acid >=95%, FCC, FG | 64-18-6 | MFCD00003297 | 1KG
Formic acid >=95%, FCC, FG | Purity: >=95% | Mol Wt: 46.03 | 64-18-6 | MFCD00003297 | 1KG
U.S. Pharmacopeia Formic Acid (1.2 mL/ampule; 3 ampules) | 64-18-6 | MFCD00003297
Formic Acid (1.2 mL/ampule; 3 ampules) | Mol Wt: 46.025 | 64-18-6 | MFCD00003297 |
Medchemexpress LLC Ammonium formate | 540-69-2 | MFCD00013103 | 98.5% | 63.06 g/mol | CH5NO2 | 100g
Formic acid ammonium salt is an endogenous metabolite
Medchemexpress LLC Ammonium formate | 540-69-2 | MFCD00013103 | 98.5% | 63.06 g/mol | CH5NO2 | 50g
Formic acid ammonium salt is an endogenous metabolite
Sigma Aldrich Fine Chemicals Biosciences Formic acid ACS reagent, >=88% | 64-18-6 | MFCD00003297 | 2.5L
Formic acid ACS reagent, >=88% | Purity: >=88% | Mol Wt: 46.03 | 64-18-6 | MFCD00003297 | 2.5L
eMolecules Oakwood Chemicals Formic Acid ACS Grade 2 5kg 480143864 093996 0 000 64-18-6 MFCD00003297 46 025 CH2O2
Oakwood Chemicals Formic Acid ACS Grade 2 5kg 480143864 093996 0 000 64-18-6 MFCD00003297 46 025 CH2O2
Sigma Aldrich Fine Chemicals Biosciences FORMIC ACID, PURISS. P.A.,2.5L
Formic Acid, puriss. p.a., ACS reagent, reag. Ph. Eur., ≥98% 2.5L
Cambridge Isotope Laboratories FORMIC ACID (OD, 98%) (, 5 G, 1925-94-0
FORMIC ACID (OD, 98%) (, 5 G, 1925-94-0
Sigma Aldrich Fine Chemicals Biosciences Formic acid puriss., meets analytical specifications of DAC, FCC, 98.0-100% | 64-18-6 | MFCD00003297 | 1L
Formic acid puriss., meets analytical specifications of DAC, FCC, 98.0-100% | Purity: 98.0-100% | Mol Wt: 46.03 | 64-18-6 | MFCD00003297 | 1L
TARGETMOL CHEMICALS INC BMS-561392 FORMIC ACID 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. BMS-561392 Formic acid is a selective inhibitor of TACE and reduces TNFalpha levels.